Search results for "optic nerve head"

showing 3 items of 3 documents

Flicker Defined Form Perimetry in Glaucoma Suspects with Normal Achromatic Visual Fields

2014

To evaluate if repeated flicker-defined form (FDF) perimetry can detect visual field (VF) defects in glaucoma suspects with normal findings in achromatic standard automated perimetry (SAP).Patients with optic nerve heads (ONHs) or retinal nerve fiber layer (RNFL) findings clinically suspicious for glaucoma and normal SAP were enrolled. Patients underwent VF testing with FDF perimetry (Heidelberg Edge Perimetry, HEP) at two consecutive visits (HEP I and HEP II) and confocal scanning laser ophthalmoscopy with the Heidelberg Retina Tomograph (HRT). Abnormal HEP was defined by cluster-point analysis (CPA) and by the HEP specific glaucoma hemi-field test (GHT). Results were compared with an age-…

AdultMaleRetinal Ganglion Cellsmedicine.medical_specialtygenetic structuresOptic DiskVision DisordersVisual AcuityNerve fiber layerGlaucomalaw.inventionTonometry OcularCellular and Molecular Neurosciencechemistry.chemical_compoundNerve FiberslawOphthalmologymedicineHumansProspective StudiesIntraocular PressureHeidelberg retina tomographOptic Nerve Headsbusiness.industryGlaucomaRetinalMiddle Agedmedicine.diseaseeye diseasesSensory SystemsVisual fieldConfocal scanning laser ophthalmoscopyOphthalmologyEarly Diagnosismedicine.anatomical_structurechemistryAchromatic lensVisual Field TestsFemaleOcular Hypertensionsense organsVisual FieldsbusinessCurrent Eye Research
researchProduct

Idiopathic intracranial hypertension: orbital MRI

1995

The case is reported of a patient with idiopathic intracranial hypertension examined with magnetic resonance imaging. Marked enhancement of the optic nerve heads was found, which might be related to blood-retinal barrier breakdown related to a sudden rise in intracranial cerebrospinal fluid pressure.

AdultMalemedicine.medical_specialtyNeurologyIntracranial PressureOptic DiskBlood–retinal barrierCentral nervous system diseaseCerebrospinal Fluid PressureBlood-Retinal BarriermedicineHumansRadiology Nuclear Medicine and imagingOptic Nerve HeadsNeuroradiologyPseudotumor Cerebrimedicine.diagnostic_testbusiness.industryMagnetic resonance imagingAnatomymedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureNeurology (clinical)RadiologyCerebrospinal fluid pressureNeurosurgeryCardiology and Cardiovascular MedicinebusinessOrbitNeuroradiology
researchProduct

Comparative Quantitative Analysis of Porcine Optic Nerve Head and Retina Subproteomes

2019

Optic nerve head (ONH) and retina (RET) are the main sites of damage in neurodegenerative optic neuropathies including glaucoma. Up to date, little is known about the molecular interplay between these two adjoining ocular components in terms of proteomics. To close this gap, we investigated ONH and RET protein extracts derived from porcine eyes (n = 12) (Sus scrofa domestica Linnaeus 1758) using semi-quantitative mass spectrometry (MS)-based proteomics comprising bottom-up LC&ndash

Proteomics0301 basic medicineretinaProteomegenetic structuresSus scrofaGlaucomaProteomicslcsh:ChemistrySus scrofa domestica0302 clinical medicineTandem Mass SpectrometryProtein Interaction Mapslcsh:QH301-705.5Spectroscopybiologyoptic nerve headGeneral MedicineComputer Science ApplicationsCell biologymedicine.anatomical_structureProteomeOptic nerveProtein Binding<i>Sus scrofa domestica</i>Optic DiskArticleCatalysisInorganic Chemistry03 medical and health sciencesmedicineMALDI-TOF MSAnimalsHumansPhysical and Theoretical ChemistryEndoplasminMolecular BiologyRetinaClusterinOrganic Chemistrymedicine.diseaseeye diseasesLC-MSglaucomaGene Ontology030104 developmental biologylcsh:Biology (General)lcsh:QD1-999Spectrometry Mass Matrix-Assisted Laser Desorption-Ionizationbiology.proteinsense organsCeruloplasmin030217 neurology & neurosurgeryInternational Journal of Molecular Sciences
researchProduct